BrainStorm: Decoding Depression Podcast
On this podcast, we decode the science of mood disorders through discussions with a leading expert in the field, Dr. Madhukar Trivedi. We’re here to change the way we think and talk about depression, in an accessible, approachable way. Created by the Center for Depression Research and Clinical Care at UT Southwestern in Dallas, TX.
On this podcast, we decode the science of mood disorders through discussions with a leading expert in the field, Dr. Madhukar Trivedi. We’re here to change the way we think and talk about depression, in an accessible, approachable way. Created by the Center for Depression Research and Clinical Care at UT Southwestern in Dallas, TX.
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The opinions expressed are our own and do not reflect those of UT Southwestern, the O’Donnell Brain Institute, the UT System, or the state.
Episodes

Sep 14, 2022
S2, Episode 2: Risk, Resilience, and Prevention
Sep 14, 2022
Sep 14, 2022
28 min
What is the difference between mental illness and mental health? How can we make the shift from being reactive to being proactive? How can we promote recovery of the whole person, rather than just treat the symptoms? In this episode, Kathryn Forbes interviews Dr. Madhukar Trivedi and Dr. Anne Fuller about strategies to reduce risk, promote resilience, and ultimately prevent depression in adolescents. Learn about the importance of early identification and about CDRC research and outreach programs that are working to improve our understanding of youth mental health.
Anne Fuller, PhD joins us from Xavier University in Cincinnati, Ohio, where she is Assistant Professor in the School of Psychology. She received her Master's and PhD in Clinical Psychology with a child family subspecialty from Loyola University, Chicago, and completed her postdoctoral research with us at the CDRC.
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Aug 31, 2022
Aug 31, 2022
40 min
Kathryn Forbes interviews Dr. Madhukar Trivedi and three special guests—a clinical psychologist, a pediatrician, and a minister—about adolescent risk and the protective factors that can prevent mood disorders and promote mental health and well-being in adolescents. Matthew Housson PhD, Early Denison MD, and Andy Stoker PhD are all fathers who, together, have nearly 60 years of experience cultivating the minds, bodies, and spirits of children, parents, and families. To learn more, visit their website www.parentingforthepresent.com and listen to the Parenting for the Present podcast where they share best-practices and up-to-date research for practical, proactive parenting.
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Dec 1, 2021
Dec 1, 2021
32 min
Catherine Huff interviews Dr. Manish Jha and Dr. Madhukar Trivedi. There has been a renewed interest in researching psychedelic-assisted psychotherapy for the treatment of depression, anxiety, and other mental health disorders. But there is still much work to be done to understand this as a potential treatment. What is the mechanism by which psychedelics may work for depression? What are the risks associated with this kind of treatment? What has the research shown? What work needs to be done to have clear evidence of benefit and safety profiles?
Dr. Jha has substantial expertise in the conduct of clinical trials and extensive clinical experience in providing care to patients with treatment-refractory psychiatric illnesses. His research uses functional neuroimaging and affective neuroscience experiments to elucidate the neurocircuit mechanisms in order to develop the next generation of circuit-specific treatments for psychiatric disorders. Dr. Jha was involved with studies investigating ketamine for people with major depressive disorder.
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Nov 17, 2021
S1, Episode 9: Integrated Health Care
Nov 17, 2021
Nov 17, 2021
30 min
Catherine Huff interviews Lisa Rigby, Executive Director of Woven Health Clinic, and our own Dr. Madhukar Trivedi, in this episode all about “Integrated Health Care.” How can we work together to better support comprehensive, integrated patient care and bring quality, affordable mental health care to communities around the country?
Woven Health is a valued partner of the CDRC’s Mood Disorders Network, having implemented the VitalSign6 program with significant success in clinics across the DFW area. Learn more about Woven Health Clinic at www.wovenhealth.org
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Nov 3, 2021
S1, Episode 8: All About TMS
Nov 3, 2021
Nov 3, 2021
38 min
Catherine Huff interviews Dr. Russell Toll, Dr. Andy Czysz, and Dr. Madhukar Trivedi in this episode "All About TMS." TMS is the acronym for transcranial magnetic stimulation. But what does that mean? How is it used as treatment for depression, and why does it work? Listen as the experts discuss.
Andrew Czysz, MD, PhD, is Assistant Professor of Psychiatry at the CDRC and UTSW’s outpatient psychiatry clinic. His research focuses on biomarker discovery for depression, as well as understanding and developing new treatments for mood and substance use disorders. In his clinical practice, Dr. Czysz evaluates and treats patients with treatment-resistant depression using innovative approaches including transcranial magnetic stimulation.
Russell Toll, PhD, is Assistant Professor of Psychiatry at the CDRC who serves as the research lead for the CDRC’s Electroencephalography (EEG) and Transcranial Magnetic Stimulation (TMS-EEG) programs. As a US Army combat veteran of the Iraq War, Dr. Toll works on solutions to depression and PTSD through his research on connectivity topographies of mood disorders.
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Oct 20, 2021
S1, Episode 7: Self-Monitoring with Evexia
Oct 20, 2021
Oct 20, 2021
28 min
Kathryn Forbes interviews Sara Levinson, MPH, MSLOC and Dr. Madhukar Trivedi about the importance of self-monitoring and the work to reduce the burdens associated with mental health screening by putting the power in the hands of individuals. Active self-monitoring helps you quickly notice changes in your mental health, so that you can quickly take action. CDRC researchers designed the Evexia self-monitoring website to empower individuals to screen themselves regularly and track changes in their mental wellness over time.
As Senior Project Manager and Head of the CDRC’s Mood Disorders Network (MDN), Sara Levinson works to implement the findings from CDRC research into real world settings. The MDN’s newest project, Evexia, is a tool developed by mental health professionals that empowers youth and adults alike to manage and monitor their mental health from anywhere, at anytime. Ready to get started? You can sign up today for this free and confidential service at www.centerfordepression.org
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Oct 6, 2021
Oct 6, 2021
25 min
Catherine Huff interviews Dr. Madhukar Trivedi, Founding Director of the CDRC, about the search to identify biosignatures for depression. What were the first biomarker research studies? What are the most promising biomarkers? What is the CDRC studying now? And how will this impact the future of depression treatment? Depression isn’t “one size fits all”, and treatment shouldn’t be, either. Listen to learn about all things biomarkers, and why it is so important to apply precision medicine to depression.
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Sep 22, 2021
S1, Episode 5: Youth Suicide Prevention Programs
Sep 22, 2021
Sep 22, 2021
29 min
This episode discusses youth suicide prevention and school-based programs. Our debut episode discussed youth depression, and now we dig in deeper with a focus on what can be done to support healthier, more resilient youth and young adults. Kathryn Forbes interviews Dr. Madhukar Trivedi, Founding Director of the CDRC, and Dr. Jennifer Hughes, Associate Professor, Licensed Psychologist, and head of the CDRC’s Risk and Resilience Network. To learn more about the Youth Aware of Mental Health program, visit y-a-m.org
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Sep 8, 2021
Sep 8, 2021
21 min
Kathryn Forbes interviews Dr. Madhukar Trivedi and Dr. Jennifer Hughes about the Texas Youth Depression and Suicide Research Network (TX-YDSRN). Funded by the state as part of the Texas Child Mental Health Care Consortium, TX-YDSRN supports important research into identifying, intervening with, and supporting suicidal adolescents and young adults as well as sharing those findings with health care systems across the state to improve care for all Texans. To learn more about the TX-YDSRN, visit tx-ydsrn.swmed.org
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc

Aug 24, 2021
S1, Episode 3: The Lone Star Prize
Aug 24, 2021
Aug 24, 2021
37 min
In June, Lyda Hill Philanthropies awarded catalytic funding to Meadows Mental Health Policy Institute (MMHPI), in partnership with the Center for Depression Research and Clinical Care (CDRC), and the Department of Global Health and Social Medicine at Harvard Medical School for the Lone Star Depression Challenge. This episode, Catherine Huff talks to Dr. Madhukar Trivedi (founding director of the CDRC) and Dr. Andy Keller (President and CEO of MMHPI) about this very exciting development and how the $10 million prize will impact the future of mental health care for all Texans. Meadows Mental Health Policy Institute: www.mmhpi.org
Follow us on podbean: utswcdrc.podbean.com
Contact us at DecodingDepressionPodcast@UTSouthwestern.edu
Learn more about the CDRC:
www.utsouthwestern.edu/labs/trivedi
www.utsouthwestern.edu/cdrc


